Perceptive Instruments Ltd., founded in 1990, develops, manufactures and supplies image analysis and data processing solutions for many areas of scientific research and industry.
The comet assay, (also known as Single Cell Gel Electrophoresis – SCGE) is a method to determine the amount of DNA damage in a single cell. This assay is used for a wide range of applications, including DNA damage and repair studies, genetic toxicology testing, biomonitoring and nutritional research.
The comet assay is a versatile technique for detecting DNA damage within a single cell. This damage is usually single- or double-strand breaks. Single cells (both eukaryotic and prokaryotic) are suspended in agarose and the damaged DNA migrates from the cell nucleus when an electric field is applied.
For a comprehensive guide to the comet assay, including useful publications and a troubleshooting guide, we recommend you take a look at www.scorecomets.com.
Comet Assay IV systems are used all over the world for a variety of applications, such as:
Comet Assay IV can score many different types of cell; regardless of species, cell size and level of DNA damage. Comet Assay IV uses the parameters defined by Olive et al on the principle of DNA damage and comets are scored appropriately.
Comet Assay IV enables you to score comets from a live video. This helps make Comet Assay IV the fastest, easiest and most accurate way to score comets.
Comet Assay IV combines accurate, repeatable results with powerful data processing and comprehensive presentation. Once you have obtained your results, you can easily process them using the Spreadsheet Generator, which is included free with every Comet Assay IV system.
Comet Assay IV connects seamlessly to Cyto Study Manager for those running comet studies to GLP standards. Cyto Study Manager integrates integrates data acquisition, auditing, reporting and study management into a single system.
Find out more about Comet Assay IV.
"Innovative software solutions for genetic toxicology assays"
Perceptive Instruments help you integrate data acquisition, auditing and reporting for your genetic toxicology assays. With over 20 years' experience, we have always delivered highly effective solutions along with excellent customer service. We have a reputation for quality and operate a quality management system to IS0 9001:2008. Over 90% of our sales are made internationally; we have extensive experience in selling, shipping, installing and supporting our products to a global market.
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